Abstracts .1 2 2004

J. Mantas (Greece)

Future trends in Health Informatics European Union initiatives


The Health Informatics field is becoming more challenging as the globalisation of economy, the advancement of the technology as well as innovative breakthroughs are being incorporated in the discipline. In Europe as well as in other countries the funding into the research areas of this field is increasing. In this paper, a brief overview of the field as well the trends of Health Informatics are discussed with respect to the new dimensions that the education of the health care professionals has to tackle in the foreseeable future.

Keywords: Biomedical Informatics, eHealth.

V. V. Domarev

Protection of the information in medical information systems:
medical secret and modern information technologists


The questions of organization of protection of the confidential information in medical information systems are considered.

Keywords: protection, confidential information, medical information system.

V. M. Buyalskyy ,V. M Danilov

Models and tools for designing of Medical Informational-Analytical System (MIAS)
of Object Shelter Rehabilitation Center


Efficient operation of complex automated diagnostic equipment of Object Shelter (SO) Rehabilitation Center requires establishment of Medical Informational-Analytical System (MIAS), which will allow (based on monitoring data processing) solution of issues related to informational support of professional personnel selection in view of OS work execution, control of personnel health, support of professional suitability, etc.
Up-to-date practical method of forming the ensemble of models for MIAS system designing is to be suggested. The method is based on the concept of high-level architectural design of automated (informational) systems. The ensemble of models is established on the basis of main set, which corresponds to procedure-oriented, object-oriented, and information-oriented methods of system designing. Each method supplements and supports the others; therefore the ensemble ensures the most complete representation of hyperspace, repertoire, and procedures of designing.
To create the model of any applied graphic notation, software of Computer Associates International Inc. company will be used, which ensures equation of all design procedures and integration of knowledge about future system all over the technological chain of designing.
Use of the method during development, support, and progress of OS Rehabilitation Center MIAS is assumed during international SIP program realization at Chernobyl NPP.

Key words: ensemble of models, method of MIAS designing.

O. Yu. Mayorov

Computer EEG past, present, future
Part 1. A history of qEEG development, the review of special methods of research


The paper is devoted to a history of qEEG development, to an estimation of a condition and prospects of the further development of this method.
In Part 1 some historical data on origin of qEEG and the brief review of modern methods of EEG research which enter into an arsenal of clinical neurophysiologists are resulted. Among them: advantages of qEEG at the classical visual analysis, technology of sleep research pathology, long-term monitoring at epilepsy, sources localization of normal and pathological EEG/EP activity (an inverse problem), digital technologies at EP/ERP registration.
The Part 2 is devoted to classical and newest mathematical methods of the
EEG / EP analysis.

Key words: quantitative EEG (qEEG), sleep researches (polysomnography), long-term EEG monitoring at epilepsy, sources localization (inverse problem), computer

V. V. Gnezditsky, E. E. Henriks, V. V. Kilikovsky, O. S. Korepina

The decision rule for the estimation of the vegetative paroxysm by skin somatic response data


Skin somatic evoked potential were examined in 33 patients with vegetative paroxysm and in 32 health subjects. For spreading practical usage of skin somatic response method in vegetative disturbance diagnosis were developed the decision rules on the base which one its possible to determine the group persons who has the risk of vegetative paroxysm. The usage of this decision rule to examine group was demonstrated that correct refer to health subject or to patients with vegetative paroxysm was 88%. Our data allowed to recommend the investigation of vegetative EP in patients with vegetative disorders.

Key words: vegetative paroxysm, risk appearance, SSEP, decision rule.

T. F. Mironova, V. A. Mironov, Y. S. Shamurov, I. M. Utochkina, A.V. Kalmykova,
V. L. Kodkin, A. N. Tarasov, E.V. Davydova, M. V. Mironov, A. M. Dubel

Clinical analysis of heart rate variability and its apparatus-program equipment


Purpose of studies during 20 years in Chelyabinsk medical academy were researches and development of rhythmocardiography (RCG) method for heart rate variability (HRV) clinical analysis, adapted to condition of the practical cardiology, hardware apparatus-program complex (APK) for it and approbation both in non-nosological cardiodiagnosis. RCG was working out on the background of da database in 42300 disease cases and 14s-years experience of the RCG using in practical medicine. Also APK CAP-RC-01-Micor was created and produced, as well as HRV analysis with evaluation wave structure of the temporary interval between heart systoles in patients with different forms of cardiovascular pathology. The main requirements were substantiated to hardware-program complex for HRV analysis. It was proved the broad possibilities of high-resolution HRV analysis for evaluation of the peripheral regulation of the pacemaker sinus node activity, which has different variants, depended on the disease pathogenesis.

Key words: heart rate variability, clinical analysis, apparatus-program equipment, variants of using.

K. P. Vorobyev

Monitoring of heart rate variability as reference method of an estimation of a functional state of an organism during hyperbaric oxygenation


The exploratory retrospective basic clinical research of the current practice which is based on the analysis of 607 clinical supervision during carrying out of 3892 sessions of hyperbaric oxygenation (HBO) at exogenous intoxications and diseases with obligate infringements of vegetative regulation. Comparison of dynamics
of thirty known parameters of heart rate variability (HRV) during HBO and reference clinical attributes of current of diseases is executed.
Dynamics of parameters HRV during HBO at various diseases depend on a sex (p <0,001), age (p <0,001), gravity of the general state (p <0,001) and diseases
(p <0,001). A lot of informative and statistically significant mathematical models and the data which show is submitted, that dynamic lines of parameters HRV are adequate criteria of functional state of an organism (FSO), allow to predict an outcome of diseases and efficiency
of treatment.
As a result of research the standardized protocol of monitoring FSO is developed during sessions of HBO according to parameters HRV and principles
of selection of optimum dozes of HBO are determined.

Key words: heart rate variability, a hyperbaric oxygenation, a functional state of an organism.

N. I. Tsirelnikov, D. A. Evseenco

Adaptive and pathological changes of the fetal-placental complex during intrauterine hypoxia after pregnancy complicated by obstetric and somatic deseases


Intrauterine hypoxia leads to violation of fetal development and pathological adaptation after birth. The purpose
of present study was to evaluate status of newborns cardiovascular system and peculiarities in their postnatal adaptation after acute and chronic fetal hypoxia. We observed on 140 children (age 1 day-3 month) from mothers with normal and complicated pregnancy. Investigation included clinical, laboratories, electrocardiografic methods and also computer analysis of cardiac rhythm (CARS) and morphologic study of placenta. We determined that light acute hypoxia caused mainly functional changes in placenta and fetal organism. This newborns had high level of simpatico-adrenal activity, which normalized during several weeks. Chronic hypoxia on early studies caused structural changes in terminal villi of placenta rise capillaries amount and area, rise amount and extent of syncitio-endothelial membranes which provided satisfactory fetal development. Severe chronic hypoxia leads to serious structural violations in placenta dystrophy and destruction of syncitial epithelium, breach of microcirculation in terminal villi, and main fetal systems. Newborns after severe chronic intrauterine hypoxia had exhaustion of simpatico-adrenal system. This pathological reaction can be considered as a foundation for different desiases wich taked place occur in this group of children.

Keywords: placenta, fetus, newborn, adaptation, hypoxia, growth retardation, computer analysis of cardiac rhythm, electrocardiography.

V. I. Shulgin, A. V. Pechenin, V. V. Fedotenko, K. V. Nasedkin, I. V. Lahno

Blind source separation technology application to fetal electrocardiogram extraction


The purpose of the work is development of effective fetal electrocardiogram (FECG) extraction algorithm on the base of a blind source separation technology.
Application of the proposed algorithm assumes a digital processing of the electrocardiogram recorded from the mother body surface. This algorithm was tested by more then 30 ECG-records
of CardioLab and CardioCE cardiographs.
The results of the work showed that the application of preprocessing in combination with blind source separation technology make it possible to produce high-quality FECG- extraction in 90% cases.

Keywords: fetal ECG extraction, Blind Source Separation (BSS), Independent Component Analysis (ICA), CardioLab, CardioCE.

A. S. Barilo, S. V. Pavlov

Optic-electronic methods of the analysis microcirculation of infringements at inflammation processes in jaw-facial region


In paper the using of photopletismograf method at the analysis of inflammation processes are considered.
The purpose of work is to show efficiency of photopletismograf method using at the analysis of a level of microcirculation periferic of vessels at inflammation processes.
As a result of researches, which were carried out on the basis of faculty of Jaw-Facial Surgery of Vinnitsa National Medical University was examined 30 (21 men and 9 women in the age of from 20 till 60 years) patients with odontogen abscess and phlegmons. The treatment of the patients included removal causal tooth, opening phlegmons or abscess, ozonetherapy with inclusion of ions of silver.
The application of the given method in stomatology allows: precisely to define efficiency of spent treatment; to specify duration reablement of the period; to reveal every possible vessel of infringement at crises jaw; to estimate efficiency local anesthesia to apply the given method
to plastic surgery and transplantology.

Keywords: photopletismogram, optic-electronic sensor control, jaw-facial region.

L. Ya. Kovalchuk, V. P. Marzeniuk

Development of system analysis methods of pathologic processes for evidence-based medicine


Evidence-based medicine states the problem of development of effective methods for modelling and analysis
of pathologic processes. In given work there is done survey of basic results obtained in this field in Ternopil State Medical Academy. Namely, there is presented applied system analysis algorithm of pathologic process, there are shown methods of investigation for such a class of dynamic systems.

Keywords: system analysis methods, dynamic system, pathologic process, evidence-based medicine.

Bekir Karlik, Yousif Al-Bastaki (Bahrain)

Bad breathe diagnosis system using OMX-GR sensor and Neural Network for telemedicine


In work the description of the developed telemedical system for diagnostics of diseases under the analysis of exhaled air odors, vapors, and gases (on the example of a sugar diabetes). The system will consist of digital sensor OM. Results of the analysis will be transformed by the sensor to the digital form and with the help of telemetry are transferred in the removed computer which has the software on the basis of neural network. The computer is trained to distinguish various aromas and them to classify, that then is used for diagnostics of a pathology (sugar diabetes).

Key words: the sensor of the analysis of odors, a telemedicine, neural networks, computer diagnostic systems.

A. V. Vladzymyrskyy, V. G. Klymovytskyy

Main stages and results of teleconsultation in clinical practice


Offered standartisation of some stages of teleconsultation, research of results
of application of different kinds of teleconsultation in clinical practice. Carried out 209 teleaconsultations. Internet-technologies to synchronous and asynchronous teleconsultation were applied. Were developed algorithm of a choice of telemedical technology and indications to realization of clinical teleconsultation. For clinical teleconsultation it is expedient to use a workstation of the following set: personal computer, digital camera, dial-up Internet channel, printer. In daily clinical practice it is most expedient to use asynchronous informal and formal teleconsultation on the basis of Internet-technologies and synchronous consultation under the circuit ICQ + e-mail. The accuracy of diagnostics of various traumas and diseases by digital data reaches 88%. The efficiency of use of the recommendations of the distant advisers makes 88,3%.

Key words: telemedicine, teleconsultation, treatment, diagnostics.

M. P. Burykh, G. V. Goryainova, S. P. Shklar, P. O. Luchshev, R. S. Voroschuk

Truly topographic approach in clinical anatomy


The article sheds the light upon problem usage of topographic approach for study of the human anatomy relative to creation computer-based virtual modeling of human internal organs, as well as propositions of future investigations and further progress in teaching of clinical anatomy are presented.

Key words: topographic anatomy, computer-based virtual modeling of human internal organs, clinical anatomy, teaching.

V. Moroz, J. Khayimzon, E. Bondarchuck

The system of computer modeling of vital functions processes of bodies and systems of the human beings organism


The system of computer simulation of the vital processes of organs and systems of human body was elaborated. In the process of its designing the modern systematic approach was used, based on mathematic simulation of the processes of human physiological activity, taking into account all intercommunications between different organs, biochemical and enzymatic transmutations in organs and tissues, influence of environment. User can model any state of human body by setting different meanings to the appropriate indicators in any subsystem will lead to automatic revise of all parameters of the system, which were connected with modeling condition. By its functional capabilities the system doesnt have analogs in medical simulators and can be widely used in tuition process at higher medical institutions, scientific medico-biological investigations, clinical practice.

Key words: computer modeling in medicine, medical simulators, medical information systems.